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2021-2023

Home 2021-2023

2023

  • FULL TEXT
    254. Bi, C.*; Wang, Y.*; He, C.; Baran, P. S. Enantioselective Total Synthesis of (+)-KB343. J. Am. Chem. Soc. accepted, 2023
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    253. Tang, J.*; Li, W.*; Chiu, T-Y.; Luo, Z.; Chong, C. T.; Wei, Q.; Martínez-Peña, F.; Gazaniga, N.; See, Y. Y.; Lairson, L. L.; Parker, C. G.; Baran, P. S. A Scalable Total Synthesis of Portimine A and B Reveals the Basis of Their Potent and Selective Anti-cancer Activity. ChemRxiv Preprint 2023

2022

Contents

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    252. Zhang, H.-J.†; Ociepa, M.†; Nassir, M.†; Zheng, B.; Lewicki, S. A.; Salmaso, V.; Babury, H.; Nagel, J.; Mirza, S.; Bueschbell, B.; Al-Hroub, H.; Perzanowska, O.; Lin, Z.; Schmidt, M. A.; Eastgate, M. D.; Jacobson, K. A.; Müller, C. E..; Kowalska, J.; Jemielity, J.; Baran, P. S. Practical Stereocontrolled Access to Thioisosteres of Essential Signaling Molecules and Building Blocks for Life: Nucleoside Di- and Triphosphates. ChemRxiv Preprint 2022
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    251. Hioki, Y.; Costantini, M.; Griffin, J.; Harper, K. C.; Merini, M. P.; Nissl, B.; Kawamata, Y.; Baran, P. S. Overcoming the Limitations of Kolbe Coupling via Waveform-Controlled Electrosynthesis. Science, accepted, 2022
  • 249. Laudadio, G.; Palkowitz, M. D.; Ewing, T. E.-H.; Baran, P. S. Decarboxylative Cross-Coupling: A Radical Tool In Medicinal Chemistry. ChemRxiv Preprint 2022
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    249. Laudadio, G.; Palkowitz, M. D.; Ewing, T. E.-H.; Baran, P. S. Decarboxylative Cross-Coupling: A Radical Tool In Medicinal Chemistry. ACS Med. Chem. Lett. 2022, 13, 9, 1413–1420
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    SUPPORTING INFORMATION
    248. Lou, T. S.-B.; Kawamata, Y.; Ewing, T.; Correa-Otero, G. A.; Collins, M. R.; Baran, P. S. Scalable, Chemoselective Ni-Electrocatalytic Sulfinylation of Aryl Halides with SO2, Angew. Chem. Int. Ed. 2022, 61, e2022080.
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    247. Lin, Y.-C.; Schneider, F.; Eberle, K, J.; Chiodi, D.; Nakamura, H.; Reisberg, S. H.; Chen, J.; Saito, M.; Baran, P. S. Atroposelective Total Synthesis of Darobactin A. J. Am. Chem. Soc. 2022, 144, 32, 14458–14462.
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    SUPPORTING INFORMATION
    246. Palkowitz, M. D., Laudadio, G.; Kolb, S.; Choi, J.; Oderinde, M. S.; Ewing, T. E.-H.; Bolduc, P.; Chen, T.; Zhang, H.; Cheng, P. T. W.; Zhang, B.; Mandler, M.; Richter, J. M.; Collins, M. R.; Schioldager, R. L.; T. G. M. Dhar; Vokits, B.; Zhu, Y.; Echeverria, P.-G.; Poss, M. A.; Shaw, S.; Clementson, S.; Petersen, N. N.; Mykhailiuk, P.; Baran, P. S. Overcoming Limitations in Decarboxylative Arylation via Ag-Ni Electrocatalysis. J. Am. Chem. Soc. 2022, 144, 38, 17709–17720.
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    SUPPORTING INFORMATION
    244. Hayashi, K.; Griffin, J.; Harper, K. C.; Kawamata, Y.; Baran, P. S. Chemoselective, Metal-free, (Hetero)Arene Electroreduction Enabled by Rapid Alternating Polarity. J. Am. Chem. Soc. 2022, 144, 13, 5762–5768
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    243. Kawamata, Y.; Ryu, K. A.; Hermann, G. N.; Sandahl, A.; Vantourout, J. C.; Olow, A. K.; Adams, L.-T., A.; Rivera-Chao, E.; Roberts, L. R.; Oslund, R. C.; Fadeyi, O. O.; Baran, P. S. Electroaffinity Labeling: A New Platform for Chemoproteomic-based Target Identification. ChemRxiv Preprint 2022
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    242. Zhang, B.; Gao, Y.; Hioki, Y.; Oderinde, M. S.; Qiao, J. X.; Rodriguez, K. X.; Zhang, H.-J.; Kawmata, Y.; Baran, P. S. Ni-Electrocatalytic C(sp3 )–C(sp3 ) Doubly Decarboxylative Coupling. Nature 2022, 606, 313–318.
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    SUPPORTING INFORMATION
    241. Gu, J.; Rodriguez, K. X.; Kanda, Y.; Yang, S.; Ociepa, M.; Wilke, H.; Abrishami, A. V.; Jørgensen, L.; Skak-Nielsen, T.; Chen, J. S.; Baran, P. S. Convergent Total Synthesis of (+)-Calcipotriol: A Scalable, Modular Approach to Vitamin D Analogs. PNAS, 2022, 119, e2200814119.
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    240. Harwood, S. J.; Palkowitz, M. D.; Gannet, C. N.; Perez, P.; Yao, Z.; Sun, L.; Abruna, H. D.; Anderson, S. L.; Baran, P. S. Modular Terpene Synthesis Enabled by Mild Electrochemical Couplings. Science 2022, 375, 745 - 752

2021

  • FULL TEXT
    239. Knouse, K. W.; Flood, D. T.; Vantourout, J. C.; Schmidt, M. A.: Mcdonald, I. M.; Eastgate, M. D.; Baran, P. S. Nature Chose Phosphates and Chemists Should Too: How Emerging P(V) Methods Can Augment Existing Strategies. ACS Cent. Sci. 2021, 7, 1473 - 1485
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    238. Gnaim, S.; Bauer, A.; Zhang, H.-J.; Chen, L.; Gannet, C.; Malapit, C. A.; Hill, D.; Vogt, D.; Tang, Tianhua, T.; Daley, R.; Hao, W.; Quertenmont, M.; Beck, W. D.; Kandahari, E.; Vantourout, J. C.; Echeverria, P.-G.; Abruna, H.; Blackmond, D.; Minteer, S.; Reisman, S.; Sigman, M. S.; Baran, P. S. Cobalt-Electrocatalytic Hydrogen Atom Transfer for Functionalization of Unsaturated C-C Bonds. Nature 2022, 605, 687
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    237. Ociepa, M.; Knouse, K. W.; He. D.; Vantourout, J. C.; Flood, D. T.; Padial, N. M.; Chen, J. S.; Sanchez, B. B.; Sturgell, E. J.; Zheng, B.; Qiu, S.; Schmidt, M. A.; Eastgate, M. D.; Baran, P. S. Mild and Chemoselective Phorsphorylation of Alcohols Using a Psi-Reagent. Org. Lett. 2021, 23, 9337 - 9342
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    236. Zhang, H.-J.; Chen, L.; Oderinde, M. S.; Edwards, J. T.; Kawamata, Y.; Baran, P. S. Chemoselective, Scalable Nickel-Electrocatalytic O-Arylation of Alcohols. Angew. Chem. Int. Ed. 2021, 60, 20700 - 20705
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    SUPPORTING INFORMATION
    235. Choi, J.; Laudadio, G.; Godineau, E.; Baran. P. S. Practical and Regioselective Synthesis of C4-Alkylated Pyridines. J. Am. Chem. Soc. 2021, 143, 11927 - 11933
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    234. Maity, P.; Anandamurthy, A. S.; Shekarappa, V.; Vaidyanathan, R.; Zheng, B.; Zhu, J.; Schmidt, M. A.; Fox, R. J.; Knouse, K. W.; Vantourout, J. C.; Baran, P. S.; Eastgate, M. D. Synthesis of a Phosphorous Sulfur Incorporating Reagent for the Enantioselective Synthesis of Thiophosphates. Org. Synth. 2021, 98, 97-116
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    Blog post
    SUPPORTING INFORMATION
    233. Huang, Y.; Knouse, K. W.; Qiu, S.; Hao, W.; Padial, N. M.; Vantourout, J. C.; Zheng, B.; Mercer, S. E.; Lopez, J. O.; Narayan, R.; Olson, R. E.; Blackmond, D. G.; Eastgate, M. D.; Schmidt, M. A.; McDonald, I. M.; Baran, P. S. A P(V)-Platform for Oligonucleotide Synthesis. Science, 2021, 373, 1265 - 1270
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    232. Kawamata, Y.; Hayashi, K.; Carlson, E.; Shaji, S.; Waldmann, D.; Simmons, B. J.; Edwards, J.; Zapf, C. W.; Saito, M.; Baran, P. S. Chemoselective Electrosynthesis Using Rapid Alternating Polarity. J. Am. Chem. Soc. 2021, 143, 16580 - 16588
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    SUPPORTING INFORMATION
    231. Gao, Y.; Hill, D. E.; Hao, W.; McNicolas, B. J.; Vantourout, J. C.; Hadt, R. G.; Reisman, S. E.; Blackmond, D.; Baran, P. S. Electrochemical Nozaki–Hiyama–Kishi Coupling: Scope, Applications, and Mechanism. J. Am. Chem. Soc. 2021, 143, 9478 - 9488
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    230. Barton, L. M.; Chen, L.; Blackmond, D.; Baran, P. S. Electrochemical Borylation of Carboxylic Acids. PNAS, 2021, 118, e2109408118
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    SUPPORTING INFORMATION
    229. Saito, M.; Kawamata, Y.; Meanwell, M.; Navratil, R.; Chiodi, D.; Carlson, E.; Hu, P.; Chen, L.; Udyavara, S.; Kingston, C.; Tanwar, M.; Tyagi, S.; McKillan, B. P.; Gichina, M. G.; Schmidt, M. A.; Eastgate, M. D.; Lamberto, M.; He, C.; Tang, T.; Malapit, C.; Sigman, M. S.; Minteer, S. D.; Neurock, M.; Baran, P. S. N-Ammonium Ylide Mediators for Electrochemical C–H Oxidation. J. Am. Chem. Soc. 2021, 143, 7859 - 7867
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    228. Peters, D. S.; Pitts, C. R.; McClymont, K. S.; Stratton, T. P.; Bi, C.; Baran, P. S. Ideality in Context: Motivations for Total Synthesis. Acc. Chem. Res. 2021, 54, 605 - 617
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    227. Gnaim, S.; Vantourout, J. C.; Serpier, F.; Echeverria, P.-G.; Baran, P. S. Carbonyl Desaturation: Where Does Catalysis Stand? ACS Catal. 2021, 11, 883 - 892

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