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2020

2019

Contents

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    209. Barton, L. M.; Edwards, J. T.; Johnson, E. C.; Bukowski, E. J.; Sausa, R. C.; Byrd, E. F. C.; Orlicki, J. A.; Sabatini, J. J.; Baran, P. S. Impact of Stereo- and Regiochemistry on Energetic Materials. J. Am. Chem. Soc. 2019, 141, 12531 - 12535
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    208. Xiang, J.; Shang, M.; Kawamata, Y.; Lundberg, H.; Reisberg, S.; Chen, M.; Mykhailiuk, P.; Beutner, G.; Collins, M.; Davies, A.; Del Bel, M.; Gallego, G.; Spangler, J.; Starr, J. T.; Yang, S.; Blackmond, D.; Baran, P. S. Hindered Dialkyl Ether Synthesis via Electrogenerated Carbocations. Nature 2019, 573, 398
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    207. Flood, D. T.; Asai, S.; Zhang, X.; Wang, J.; Yoon, L.; Adams, Z. C.; Dillingham, B. C.; Sanchez, B.; Vantourout, J. C.; Flanagan, M. E.; Piotrowski, D. W.; Richardson, P.; Green, S.; Shenvi, R.; Chen, J.; Baran, P. S.; Dawson, P. Expanded Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support. J. Am. Chem. Soc. 2019, 141, 9998
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    206. Ni, S.; Padial, N. M.; Kingston, C.; Vantourout, J. C.; Schmitt, D. C.; Edwards, J. T.; Kruszyk, M.; Merchant, R. R.; Mykhailiuk, P. K.; Sanchez, B.; Yang, S.; Perry, M.; Gallego, G. M.; Mousseau, J. J.; Collins, M. R.; Cherney, R. J.; Lebed, P. S.; Chen, J. S.; Qin, T.; Baran, P. S. A Radical Approach to Anionic Chemistry: Synthesis of Ketones, Alcohols, and Amines. J. Am. Chem. Soc. 2019, 141, 6726.
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    205. Takahira, Y.; Chen, M.; Kawamata, Y.; Mykhailiuk, P.; Nakamura, H. Peters, B. K.; Reisberg, S. H.; Li, C.; Chen, L.; Hoshikawa, T.; Shibuguchi, T.; Baran, P. S. Electrochemical C(sp3)-H Fluorination. Synlett, 2019, 30, 1178
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    204. Kawamata, Y.; Vantourout, J. C.; Hickey, D. P.; Bai, P.; Chen, L.; Hou, Q.; Qiao, W.; Barman, K.; Edwards, M. A.; Garrido-Castro, A. F.; deGruyter, J. N.; Nakamura, H.; Knouse, K.; Qin, C.; Clay, K. J.; Bao, D.; Li, C.; Starr, J. T.; Garcia-Irizarry, C.; Sach, N.; White, H. S.; Neurock, M.; Minteer, S. D.; Baran, P. S. Electrochemically Driven, Ni-Catalyzed Aryl Amination: Scope, Mechanism, and Applications. J. Am. Chem. Soc. 2019, 141, 6392.
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    203. Peters, B. K.; Rodriguez, K. X., Reisberg, S. H.; Beil, S. B.; Hickey, D. P.; Kawamata, Y.; Collins, M.; Starr, J.; Chen, L.; Udyavara, S.; Klunder, K.; Gorey, T. J.; Anderson, S. L.; Neurock, M.; Minteer, S. D.; Baran, P. S. Scalable and Safe Synthetic Organic Electroreduction Inspired by Li-Ion Battery Chemistry. Science 2019, 363, 838
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    202. Shang, M.; Feu, K. S.; Vantourout, J. C.; Barton, L. M.; Osswald, H. L.; Kato, N.; Gagaring, K.; McNamara, C. W.; Chen, G.; Hu, L.; Ni, S.; Fernández-Canelas, P.; Chen, M.; Merchant, R. R.; Qin, T.; Schreiber, S.; Melillo, B.; Yu, J.-Q.; Baran, P. S. Modular, Stereocontrolled Cβ–H/Cα–C Activation of Alkyl Carboxylic Acids. PNAS, 2019, 116, 8721
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    201. Nakamura, H.; Yasui, K; Kanda, Y.; and Baran, P. S. 11-Step Total Synthesis of Teleocidins B-1–B-4. J. Am. Chem. Soc. 2019, 141, 1494.
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    200. Chen, T. -G.; Zhang, H.; Mykhailiuk, P. K.; Merchant, R. R.; Smith, C. A.; Qin, T.; Baran, P. S. Quaternary Centers via Ni-Catalyzed Cross-Coupling of Tertiary Carboxylic Acids and Aryl Zinc Reagents. Angew. Chem. Int. Ed. 2019, 58, 2454.
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    199. He, C.; Stratton, T. P.; Baran, P. S. Concise Total Synthesis of Herqulines B and C. J. Am. Chem. Soc. 2019, 141, 29.
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    198. Kingston, C.; Wallace, M; Allentoff, A. J.; deGruyter, J.; Chen, J.; Gong, S.; Bonacorsi, S. Jr.; Baran, P. S. Direct Carbon Isotope Exchange Through Decarboxylative Carboxylation. JACS, 2019, 141, 2, 774.

2018

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    197. Smith, J.; Dixon, J.; deGruyter, J. N.; Baran, P. S. Alkyl Sulfinates: Radical Precursors Enabling Drug Discovery. J. Med. Chem. 2018, 62, 2256
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    196. Ni, S.; Garrido-Castro, A. F.; Merchant, R. R.; deGruyter, J. N.; Schmitt, D. C.; Mousseau, J. J.; Gallego, G. M.; Yang, S.; Collins, M. R.; Qiao, J. X.; Yeung, K.; Langley, D. R.; Poss, M. A.; Scola, P. M.; Qin, T.; Baran, P. S. A General Amino Acid Synthesis Enabled by Innate Radical Cross-Coupling, Angew. Chem. Int. Ed. 2018, 57, 14560.
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    195. Wang, J.; Shang, M.; Lundberg, H.; Feu, K. S.; Hecker, S. J.; Qin, T.; Blackmond, D. G.; Baran, P. S. Cu-Catalyzed Decarboxylative Borylation. ACS Catal. 2018, 8, 9537.
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    194. Knouse, K. W.; deGruyter, J. N.; Schmidt, M. A.; Zheng, B.; Vantourout, J. C.; Kingston, C.; Mercer, S. E.; Mcdonald, I. M.; Olson, R. E.; Zhu, Y.; Hang, C.; Zhu, J.; Yuan, C.; Wang, Q.; Park, P.; Eastgate, M. D.; Baran, P. S. Unlocking P(V): Reagents for chiral phosphorothioate synthesis. Science, 2018, 361, 1234
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    193. Smith, J. M.; Harwood, S. J.; Baran, P. S. Radical Retrosynthesis. Acc. Chem. Res. 2018, 51, 1807.
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    192. Chen, T. –G.; Barton, L. M.; Lin, Y.; Tsien, J.; Kossler, D.; Bastida, I.; Asai, S.; Bi, C.; Chen, J. S.; Shan, M.; Fang, H.; Fang, F. G.; Choi, H. –W.; Hawkins, L.; Qin, T.; Baran, P. S. Building C(sp3)-rich complexity by combining cycloaddition and C–C cross-coupling reactions. Nature, 2018, 560, 350-354.
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    191. Merchant, R. R.; Oberg, K. M.; Lin, Y.; Novak, A. J. E.; Felding, J.; Baran, P. S. Divergent Synthesis of Pyrone Diterpenes via Radical Cross Coupling. J. Am. Chem. Soc. 2018, 140, 7462.
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    190. Wang, J.; Lundberg, H.; Asai, S.; Martín-Acosta, P.; Chen, J. S.; Brown, S.; Farrell, W.; Dushin, R.; O’Donnell, C. J.; Ratnayake, A. S.; Richardson, P.; Liu, Z.; Qin, T.; Blackmond, D. G.; Baran, P. S. Kinetically Guided Radical-Based Synthesis of C(sp3)-C(sp3) Linkages on DNA. PNAS, 2018, 115, E6404.
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    189. Baran, P. S. Natural Product Total Synthesis: As Exciting as Ever and Here To Stay. J. Am. Chem. Soc. 2018, 140, 4751.
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    188. Chu, H.; Dünstl, G.; Felding, J.; Baran, P. S. Divergent synthesis of thapsigargin analogs. Bioorg. Med. Chem. Lett. 2018, Bioorg. Med. Chem. Lett. 2018, 28, 2705.
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    187. Peters, D.; Romesberg, F. E.; Baran, P. S. Scalable Access to Arylomycins via C–H Functionalization Logic. J. Am. Chem. Soc. 2018, 140, 2072.
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    186. Merchant, R. R.; Edwards, J. T.; Qin, T.; Kruszyk, M. M.; Bi, C.; Che, G.; Bao D-H.; Qiao, W.; Sun, L.; Collins, M. R.; Gallego, G. M.; Mousseau, J. J.; Nuhant, P.; Baran, P. S. Modular radical cross-coupling with sulfones enables access to sp3-rich (fluoro)alkylated scaffolds. Science, 2018, 360, 75.

2017