2016
Table of Contents
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168. Tian, M.; Yan, M.; Baran, P. S. 11-Step Total Synthesis of Araiosamines, J. Am. Chem. Soc. 2016, 138, 14234-14237 -
167. Yan, M.; Lo, J. C.; Edwards, J. T.; Baran, P. S. Radicals: Reactive Intermediates with Translational Potential, J. Am. Chem. Soc. 2016, 138, 12692-12714
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166. Toriyama, F.; Cornella, J.; Wimmer, L.; Chen, T.-G.; Dixon, D. D.; Creech, G.; Baran, P. S. Redox-Active Esters in Fe-catalyzed C-C Coupling, J. Am. Chem. Soc. 2016, 138, 11132-11135
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165. Cernijenko, A.; Risgaard, R.; Baran, P. S. 11-Step Total Synthesis of (-)-Maoecrystal V, J. Am. Chem. Soc. 2016, 138, 9425-9428
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164. Wang, J.; Qin, T.; Chen, T.-E.; Wimmer, L.; Edwards, J. T.; Cornella, J.; Vokits, B.; Shaw, S. A.; Baran, P. S. Nickel-Catalyzed Cross-Coupling of Redox-Active Esters with Boronic Acids, Angew. Chem. Int. Ed. 2016, 55, 9676-9679
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163. Martinez, L. P.; Umemiya, S.; Wengryniuk, S. E.; Baran, P. S. 11-Step Total Synthesis of Pallambins C and D, J. Am. Chem. Soc. 2016, 138, 7536-7539
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162. Yuan, C.; Jin, Y.; Wilde, N. C.; Baran, P. S. Short, Enantioselective Total Synthesis of Highly Oxidized Taxanes, Angew. Chem. Int. Ed., 2016, 55, 8280-8284
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161. Horn, E. J.; Rosen, B. R.; Baran, P. S. Synthetic Organic Electrochemistry: An Enabling and Innately Sustainable Method, ACS Cent. Sci., 2016, 2, 302-308.
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160. Qin, T.; Cornella, J.; Li, C.; Malins, L. R.; Edwards, J. T.; Kawamura, S.; Maxwell, B. D.; Eastgate, M. D.; Baran, P. S. A General Alkyl-Alkyl Cross-Coupling Enabled by Redox-Active Esters and Alkylzinc Reagents, Science, 2016, 352, 801-805
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159. Horn, E. J.; Rosen, B. R.; Chen, Y.; Tang, J.; Chen, K.; Eastgate, M. D.; Baran, P. S. Scalable and sustainable electrochemical allylic C-H oxidation, Nature, 2016, 533, 78-81
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158. Kawamura, S.; Chu, H.; Felding, J.; Baran, P. S. Nineteen-step total synthesis of (+)-phorbol, Nature, 2016, 532, 90-93
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157. Cornella, J.; Edwards, J. T.; Qin, T.; Kawamura, S.; Wang, J. Pan, C-M.; Gianatassio, R.; Schmidt, M. A.; Eastgate, M. D.; Baran, P. S. Practical Ni-Catalyzed Aryl-Alkyl Cross-Coupling of Secondary Redox-Active Esters, J. Am. Chem. Soc., 2016, 138 (7), pp 2174-2177
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156. Gianatassio, R.; Lopchuk, J. M.; Wang, J.; Pan, C-M.; Malins, L. R.; Prieto, L.; Brandt, T. A.; Collins, M. R.; Gallego, G. M.; Sach, N. W.; Spangler, J. E.; Zhu, H.; Baran, P. S. Strain-release amination, Science, 2016, 351, pp. 241-246
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155. Villaume, M.T.; Sella, E.; Saul, G.; Borzilleri, R. M.; Fargnoli, J.; Johnston, K. A.; Zhang, H.; Fereshteh, M. P.; Dhar, T. G. M.; Baran, P. S. Antroquinonol A: Scalable Synthesis and Preclinical Biology of a Phase 2 Drug Candidate, ACS Cent. Sci., 2016, 2 (1), pp 27-31
2015
Table of Contents
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154. See, Y. Y.; Herrmann, A. T.; Aihara, Y.; Baran, P. S. Scalable C-H Oxidation with Copper: Synthesis of Polyoxypregnanes, J. Am. Chem. Soc, 2015, 137, 13776-13779
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153. Jin, Y.; Yeh, C.-H.; Kuttruff, C. A.; Jorgensen, L.; Dunstl, G.; Felding, J.; Natarajan, S. R.; Baran, P. S. C-H Oxidation of Ingenanes Enables Potent and Selective Protein Kinase C Isoform Activation, Angew. Chem. Int. Ed., 2015, 54, 14044-14048
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152. Feng, Y.; Holte, D.; Zoller, J.; Umemiya, S.; Simke, L. R.; Baran, P. S. Total Synthesis of Verruculogen and Fumitremorgin A Enabled by Ligand-Controlled C-H Borylation, J. Am. Chem. Soc, 137, 10160-10163
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151. Dao, H. T.; Li, C.; Michaudel, Q.; Maxwell, B. D.; Baran, P. S. Hydromethylation of Unactivated Olefins, J. Am. Chem. Soc, 2015, 137, 8046-8049
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150. Gui, J.; Pan, C-M.; Jin, Y.; Qin, T.; Lo, J. C.; Lee, B. J.; Spergel, S. H.; Mertzman, M. E.; Pitts, W. J.; La Cruz, T. E.; Schmidt, M. A.; Darvatkar, N.; Natarajan, S. R.; Baran, P. S. Practical Olefin Hydroamination with nitroarenes, Science 2015, 348, 886–891
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149. Michaudel, Q.; Ishihara, Y.; Baran, P. S. Academia–Industry Symbiosis in Organic Chemistry, Acc. Chem. Res. 2015, 48, 712–721
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148. Renata, H.; Zhou, Q.; Dünstl, G.; Felding, J.; Merchant, R. R.; Yeh, C.-H.; Baran, P. S. Development of a Concise Synthesis of Ouabagenin and Hydroxylated Corticosteroid Analogues, J. Am. Chem. Soc. 2015, 137,1330–1340
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146. Maimone, T. J.; Ishihara, Y.; Baran, P. S. Scalable Total Syntheses of (−)-Hapalindole U and (+)-Ambiguine H, Tetrahedron 2015, 71, 3652–3665
2014
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147. Lo, J. C.; Gui, J.; Yabe, Y.; Pan, C. -M.; Baran, P. S. Functionalized Olefin Cross-Coupling to Construct Carbon-Carbon Bonds, Nature 2014, 343–348.
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145. Dao, H. T.; Baran, P. S. Quinone Diazides for Olefin Functionalization, Angew. Chem. Int. Ed. 2014, 14382–14386.
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144. Rodriguez, R. A.; Barrios Steed, D.; Kawamata, Y.; Su, S.; Smith, P. A.; Steed, T. C.; Romesberg, F. E.; Baran, P. S. Axinellamines as Broad-Spectrum Antibacterial Agents: Scalable Synthesis and Biology, J. Am. Chem. Soc. 2014, 136, 15403-15413.
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143. Michaudel, Q.; Journot, G.; Regueiro-Ren, A.; Goswami, A.; Guo, Z., Tully, T. P., Zou, L., Ramabhadran, R. O., Houk, K. N., Baran, P. S. Improving Physical Properties via C–H Oxidation: Chemical and Enzymatic Approaches, Angew. Chem. Int. Ed. 2014, 53, 12091-12096.
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142. O'Brien, A. G.; Maruyama, A.; Inokuma, Y.; Fujita, M.; Baran, P. S.; Blackmond, D. G. Radical C–H Functionalization of Heteroarenes under Electrochemical Control, Angew. Chem. Int. Ed. 2014, 53, 11868-11871.
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141. Cherney, E. C.; Lopchuk, J. M.; Green, J. C.; Baran, P. S. A Unified Approach to ent-Atisane Diterpenes and Related Alkaloids: Synthesis of (–)-Methyl Atisenoate, (–)-Isoatisine, and the Hetidine Skeleton, J. Am. Chem. Soc. 2014, 136, 12592-12595.
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140. Gianatassio, R.; Kawamura, S.; Eprile, C. L.; Foo, K.; Ge, J.; Burns, A. C.; Collins, M. R.;Baran, P. S. Simple Sulfinate Synthesis Enables C-H Trifluoromethylcyclopropanation, Angew. Chem. Int. Ed. 2014, 53, 9851-9855.
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139. Rodriguez, R. A.; Pan, C. -M.; Yabe, Y.; Kawamata, Y.; Eastgate, M. D.; Baran, P. S. Palau'chlor: A Practical and Reactive Chlorinating Reagent J. Am. Chem. Soc. 2014, 136, 6908-6911.
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138. Rosen, B. R.; Werner, E. W.; O'Brien, A. G.; Baran, P. S. Total Synthesis of Dixiamycin B by Electrochemical Oxidation J. Am. Chem. Soc. 2014, 136, 5571-5574.
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137. McKerrall, S. J.; Jorgensen, L.; Kuttruff, C. A.; Ungeheuer, F.; Baran, P. S. Development of a Concise Synthesis of (+)-Ingenol J. Am. Chem. Soc. 2014, 136, 5799-5810.
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136. Foo, K.; Sella, E.; Thome, I.; Eastgate, M. D.; Baran, P. S. A Mild, Ferrocene-catalyzed C-H Imidation of (Hetero)Arenes J. Am. Chem. Soc. 2014, 136, 5279-5282.
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135. Wilde, N. C.; Isomura, M.; Mendoza, A.; Baran, P. S. Two-Phase Synthesis of (–)-Taxuyunnanine D. J. Am. Chem. Soc. 2014, 136, 4909-4912.
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134. Gui, J.; Zhou, Q.; Pan, C.-M.; Yabe, Y.; Burns, A. C.; Collins, M. R.; Ornelas, M. A.; Ishihara, Y.; Baran, P. S. A C–H Methylation Reaction of Heteroarenes Inspired by Radical SAM Methyl Transferase. J. Am. Chem. Soc. 2014, 136, 4853-4856.
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133. Gutekunst, W. R.; Baran, P. S. Applications of C–H Functionalization Logic to Cyclobutane Synthesis. J. Org. Chem. 2014, 79, 2430-2452.
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132. O’Hara, F.; Burns, A. C.; Collins, M. R.; Dalvie, D.; Ornelas, M. A.; Vaz, A. D. N.; Fujiwara, Y.; Baran, P. S. A Simple Litmus Test for Aldehyde Oxidase Metabolism of Heteroarenes. J. Med. Chem. 2014, 57, 1616-1620.
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131. Lo, J. C. ; Yabe, Y.; Baran, P.S. A Practical and Catalytic Reductive Olefin Coupling, J. Am. Chem. Soc. 2014, 136, 1304-1307.
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130. Kuttruff, C. A.; Eastgate, M. D.; Baran, P.S. Natural Product Synthesis in the Age of Scalability, Nat. Prod. Rep. 2014, 31, 419-432.